
A retrospective study develops a nomogram combining BRAF V600E, serum biomarkers, and ultrasound features to stratify malignancy risk in C-TIRADS 3 and 4 thyroid nodules.
Key Takeaways
- Although only about 5–15% of nodules found on ultrasound are cancerous ( 2 )
- Ultrasound serves as the first-line tool when a thyroid lump is suspected
- However, their malignancy risk varies widely, from 2 to 90% ( 3 ), and their optimal management is still debated
