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SPRIN2D nomogram: predicting 90-day unfavorable outcomes in patients with minor ischemic stroke receiving intravenous thrombolysis

Source: Frontiers - Health • Published: 03 Aug 2026, 00:00

SPRIN2D nomogram: predicting 90-day unfavorable outcomes in patients with minor ischemic stroke receiving intravenous thrombolysis

A clinical research article presenting a nomogram-based prediction tool for clinicians to assess 90-day risk of unfavorable outcomes after IV thrombolysis in minor ischemic stroke patients, helping guide early decision-making and resource use.

Key Takeaways
  • Data were extracted from the Multicenter Clinical Trial of Revascularization Treatment for Acute Ischemic Stroke (TRAIS)
  • While several clinical trials have demonstrated the potential benefits of IVT in this population ( 12 )
  • Previous studies have identified multiple factors associated with unfavorable outcomes in MIS patients undergoing IVT
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