Longevity News

Neutrophil percentage-to-albumin ratio is associated with low muscle mass risk in rheumatoid arthritis: evidence from a hospital-based cohort and NHANES validation

Source: Frontiers - Health • Published: 31 Jul 2026, 00:00

Neutrophil percentage-to-albumin ratio is associated with low muscle mass risk in rheumatoid arthritis: evidence from a hospital-based cohort and NHANES validation

An observational analysis linking a composite inflammation and nutrition biomarker to low muscle mass risk in rheumatoid arthritis patients and population validation.

Key Takeaways
  • Patients with high NPAR showed significantly higher LMM prevalence than those with low NPAR
  • NPAR demonstrated strong discriminatory ability (AUC = 0.80, optimal cutoff = 9.55)
  • Additionally, higher NPAR was associated with increased all-cause mortality in RA patients with LMM during follow-up
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