A study reports green synthesis of silver nanoparticles using a microalga extract and examines their effects on human colon cancer cells, focusing on cell death pathways.
Key Takeaways
- Biosynthesized silver nanoparticles measured 10–25 nm with a zeta potential of −19.8 mV
- Nanoparticles showed an IC50 of 6.25 µg/mL against Caco-2 cells after 72 hours
- Treatment upregulated Bax, Beclin-1, and ATG5 while downregulating Bcl-2, indicating apoptosis and autophagy activation