Masters of Longevity - The Pulse

Longevity Technology04 Sept 2026
Pig kidneys just bought humans extra years in eGenesis study (Longevity Technology)

Pig kidneys just bought humans extra years in eGenesis study

Genetically engineered pig kidneys as a bridge therapy for people with kidney failure; a news feature that explains the study approach and patient implications.

Key takeaways
  • Five patients received the engineered pig kidney EGEN-2784 under expanded access in the study.
  • Three patients maintained kidney function for more than eight months without dialysis.
  • Two patients later received human donor kidneys after initial xenotransplantation success.
Nature - Biotechnology04 Sept 2026
AIDroplet digital PCR reveals that transgene copy number determines lifespan in SOD1G93A ALS mice (Nature - Biotechnology)

Droplet digital PCR reveals that transgene copy number determines lifespan in SOD1G93A ALS mice

A methods-focused research article examining how a precise DNA quantification technique maps transgene copy variation to disease trajectory in an ALS mouse model.

Key takeaways
  • Droplet digital PCR (ddPCR) quantified SOD1 G93A transgene copies between 51.68 and 119.5 copies per mouse.
  • Real-time qPCR reported lower copy ranges of 23 to 44.65 and still identified genotype reliably.
  • DdPCR copy number correlated significantly with disease phenotype and lifespan in SOD1 G93A mice.
Frontiers - Health04 Sept 2026
AISynergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and d

Synergistic effect of insulin resistance and glycemic variability on mortality in ICU patients with gastrointestinal bleeding: impact of the TyG-GVI index and development of an explainable web-based clinical calculator

This study evaluates a combined triglyceride-glucose and glycemic variability index as a prognostic tool for early mortality among ICU patients with gastrointestinal bleeding.

Key takeaways
  • Study data were extracted from the MIMIC-IV (release 3.1).
  • This archive spans 94,458 ICU-stay episodes recorded between 2008 and 2022.
  • Such static metrics may fail to capture temporal changes in metabolic instability.
MoL Event Pick
International Longevity Summit Madrid 2026 (Madrid, Spain)

International Longevity Summit Madrid 2026

28. SEPT 2026 - 1. OCT 2026 - Madrid, SpainSummit

Madrid summit convening global longevity thinkers, clinicians and innovators across four days of science, networking and public-facing programming.

Fitt Insider - Press Releases03 Sept 2026
Cymbiotika Partners with Hundred Health to Bring Personalized Health Intelligence to Its Community (Fitt Insider - Press Releases)

Cymbiotika Partners with Hundred Health to Bring Personalized Health Intelligence to Its Community

Personalized health data integration: a consumer wellness brand teams with a health-intelligence provider to offer customers tailored plan recommendations and data-driven guidance.

Key takeaways
  • Cymbiotika will integrate biomarker testing with medical history and wearable data for customers.
  • Collaboration aims to deliver personalized health plans to Cymbiotika's community.
  • Hundred Health will provide the health intelligence platform powering the data integration.