Masters of Longevity - The Pulse

Lifespan.io07 Sept 2026
Mice With Growth Hormone Halted in Middle Age Live Longer (Lifespan.io)

Mice With Growth Hormone Halted in Middle Age Live Longer

Covers research testing midlife interruption of growth hormone signaling in mice and its sex-specific effects on lifespan and physiology.

Key takeaways
  • GHR knockout produced substantial IGF-1 reductions, with the effect stronger in males.
  • Midlife knockout of the growth hormone receptor extended mouse lifespan, especially in females.
  • Male knockouts improved insulin sensitivity and preserved vertebral trabecular bone integrity.
Science Daily - Health & Medicine06 Sept 2026
Popular brain supplement linked to shorter lifespan in men (Science Daily - Health & Medicine)

Popular brain supplement linked to shorter lifespan in men

Blood-chemistry research examining links between an amino-acid supplement and male lifespan; a concise preview of methods and implications to expect.

Key takeaways
  • Higher circulating tyrosine levels are associated with a modestly reduced lifespan in men based on cohort analyses and genetic evidence.
  • Mendelian randomization suggests a potential causal link between elevated tyrosine and shorter male longevity, after accounting for confounders.
  • No consistent association between tyrosine levels and lifespan was observed in women, indicating possible sex-specific effects.
Longevity Technology04 Sept 2026
Pig kidneys just bought humans extra years in eGenesis study (Longevity Technology)

Pig kidneys just bought humans extra years in eGenesis study

Genetically engineered pig kidneys as a bridge therapy for people with kidney failure; a news feature that explains the study approach and patient implications.

Key takeaways
  • Five patients received the engineered pig kidney EGEN-2784 under expanded access in the study.
  • Three patients maintained kidney function for more than eight months without dialysis.
  • Two patients later received human donor kidneys after initial xenotransplantation success.