Masters of Longevity - The Pulse

Frontiers - Health09 Sept 2026
AIEffects and exercise-prescription moderators of Tai Chi on cardiometabolic risk factors in middle-aged and older women: a systematic review and meta-analysis (F

Effects and exercise-prescription moderators of Tai Chi on cardiometabolic risk factors in middle-aged and older women: a systematic review and meta-analysis

Tai Chi research for middle-aged and older women that reviews effects on blood pressure, lipids, glucose, and possible exercise-prescription moderators.

Key takeaways
  • Tai Chi reduced systolic blood pressure with an SMD of -0.78.
  • Significant reductions were reported for diastolic blood pressure.
  • No clear effects were found on HDL cholesterol or fasting blood glucose.
Nature - Main09 Sept 2026
Neocortical long-range inhibition promotes cortical synchrony and sleep - Nature (Nature - Main)

Neocortical long-range inhibition promotes cortical synchrony and sleep - Nature

Assessment of a rare long-range inhibitory neuron class in mouse neocortex, including anatomical mapping and behavioral-state activity.

Key takeaways
  • Sleep and wakefulness are associated with distinct cortical patterns of rhythmic activity 1.
  • Although inhibitory neurons are increasingly recognized as key regulators of cortical state 2.
  • Here we show in mice that cells co-expressing somatostatin (Sst).
Fight Aging!08 Sept 2026
AIThe Adaptive Cost Hypothesis of Aging, a Viewpoint on Antagonist Pleiotropy (Fight Aging!)

The Adaptive Cost Hypothesis of Aging, a Viewpoint on Antagonist Pleiotropy

A viewpoint reframing aging by examining evolutionary trade-offs and adaptive responses that influence late-life disease development.

Key takeaways
  • Selection pressure that drives the spread of changes in genes.
  • This inevitably gives rise to systems that perform well initially, but which fall apart later.
  • Aging is a near universal side-effect of evolutionary competition.
Nature - Main09 Sept 2026
Bacteria recruited to treat cancer (Nature - Main)

Bacteria recruited to treat cancer

Engineered bacteria as living drug factories and delivery vehicles for targeting tumors and recent advances shaping the field.

Key takeaways
  • These six advances could change how drugs are delivered Outlook 09 SEP 26 Special delivery.
  • Anticancer drugs could be manufactured and delivered by modified microorganisms.
  • View all journals This article is part of Nature Outlook.