Masters of Longevity - The Pulse

Fight Aging!01 Jun 2026
AIYet Another Proposed Definition for Allostatic Load (Fight Aging!)

Yet Another Proposed Definition for Allostatic Load

A look at a new proteomics-based definition of allostatic load and its reported predictive advantages over traditional biomarker panels.

Key takeaways
  • ProAL50 was constructed from 50 circulating proteins using UK Biobank plasma proteomics.
  • Validation in CARDIA showed stronger prediction of cancer, diabetes, heart disease, lung and kidney disease.
  • Protein signals primarily mapped to lipid metabolic and immune-inflammatory biological pathways.
Longevity Technology01 Jun 2026
AIRubedo reports promising early trial results for anti-aging skin cream (Longevity Technology)

Rubedo reports promising early trial results for anti-aging skin cream

Report on preliminary clinical data for a novel topical anti-aging cream showing safety and early efficacy signals in treatment of sun-damaged skin.

Key takeaways
  • Topical RLS-1496 1% cream reduced actinic keratosis lesions by 46% at four weeks.
  • Untreated control lesions decreased by 11% over the same four-week period.
  • Study reported favorable safety with no serious adverse events or discontinuations.
PR Newswire01 Jun 2026
ASCO 2026 | Oricell (PR Newswire)

ASCO 2026 | Oricell

Oncology conference highlights a biotech's CAR-T update for advanced liver cancer, offering fresh clinical context, safety insights, and manufacturing details.

Key takeaways
  • CAR-T achieved a 66.7% objective response rate in late-line HCC patients.
  • Disease control rate approached 90% among 18 efficacy-evaluable patients at RP2D.
  • No ICANS or off-tumor toxicity was observed and CRS was controllable.
Longevity Technology01 Jun 2026
AIElysium launches physician-led longevity program (Longevity Technology)

Elysium launches physician-led longevity program

Consumer supplement company unveils a new clinical longevity program, an upbeat company announcement describing expanded patient focused services, therapies, and ongoing clinical support.

Key takeaways
  • Enrollment is initially capped at 10,000 patients with enrollment expected in Q3 2026.
  • New physician-led longevity program offers personalized supplement and prescription protocols.
  • Program will be led by chief medical officer Omar Baker, M.D.