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SHH-functionalized fibrin scaffold improves spinal cord repair in rats and modulates primary neural stem cell behavior in vitro

Source: Nature - Biotechnology • Published: 02 Sept 2026, 00:00

SHH-functionalized fibrin scaffold improves spinal cord repair in rats and modulates primary neural stem cell behavior in vitro

Covers development of a polydopamine-modified fibrin scaffold that sustains sonic hedgehog delivery to support spinal cord repair and influence neural stem cells in vitro.

Key Takeaways
  • It is citable and carries a permanent DOI
  • This version is subject to further edits and will be replaced automatically by the final Version of Record
  • PD modification increased the SHH loading efficiency from 51.2% to 70.6%
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