SEQURNA-focused methods article presenting a comparative benchmark of a synthetic thermostable RNase inhibitor for improved single-cell, full-length RNA-seq workflows.
Key Takeaways
- SEQURNA increased gene detection by 12–15% versus a commercial RNase inhibitor in retinal organoids and PBMCs
- DTT at standard concentrations (5–10 mM) impaired gene detection and did not improve RNA quality metrics
- SEQURNA maintained sample stability after one month at −80°C and cut reagent costs by over 75%