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A CRISPR-based ‘dam-break drainage’ sensing architecture for rapid, affordable and ultrasensitive pathogen detection

Source: Nature - Biotechnology • Published: 22 Aug 2026, 00:00

A CRISPR-based ‘dam-break drainage’ sensing architecture for rapid, affordable and ultrasensitive pathogen detection

A chip-based CRISPR-Cas13a fluidic sensor translates target RNA into a visible dam-break drainage signal for rapid, instrument-free detection.

Key Takeaways
  • It is citable and carries a permanent DOI
  • This version is subject to further edits and will be replaced automatically by the final Version of Record
  • Nucleic acid testing is important for infectious-disease diagnosis
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