Describes a human 3D innervated cardiac tissue model combining sympathetic trunk–patterned neural organoids with iPSC cardiomyocytes to study neurocardiac interactions and arrhythmia drivers.
Key Takeaways
- Human tissue engineering in combination with induced pluripotent stem cells (iPSCs)
- Number of tissue-engineered and organoid models of brain 14
- Design principle in heart models is the co-culture of CMs with non-myocytes