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Bone mineral density and trabecular bone score in adults with primary immunodeficiencies: a cross-sectional study

Source: Frontiers - Health • Published: 26 Aug 2026, 00:00

Bone mineral density and trabecular bone score in adults with primary immunodeficiencies: a cross-sectional study

Assessments of bone density, trabecular microstructure, and muscle mass in adults with primary immunodeficiencies reveal bone health burdens and clinical associations.

Key Takeaways
  • Osteoporosis or fragility fractures affected 24.6% of the 61 adult PID patients studied
  • Partially degraded or degraded trabecular bone score was observed in 24.6% of participants
  • Lower muscle mass correlated with significantly reduced BMD at all measured skeletal sites
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