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Gut health and microbiome modulation by the heat-killed postbiotic beLP1® in adults with excess weight: a randomized, placebo-controlled trial

Source: Frontiers - Health • Published: 21 Aug 2026, 00:00

Gut health and microbiome modulation by the heat-killed postbiotic beLP1® in adults with excess weight: a randomized, placebo-controlled trial

Report on an 84-day randomized trial testing a heat-killed Lactiplantibacillus plantarum postbiotic for improving gut symptoms, stress, and microbiome composition in adults with excess weight.

Key Takeaways
  • This predefined analysis directly compares the beLP1® and placebo arms using analysis of covariance (ANCOVA)
  • Primary endpoint was change in gastrointestinal symptoms via the GSRS
  • BeLP1® significantly reduced total Gastrointestinal Symptom Rating Scale (GSRS)
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