Masters of Longevity - The Pulse

Nature - Biotechnology23 Oct 2026
Elizabeth Holmes film enthralls — but her legacy haunts science (Nature - Biotechnology)

Elizabeth Holmes film enthralls — but her legacy haunts science

Researchers report the Theranos scandal reduced trust in diagnostics and affects current blood-testing efforts.

Key takeaways
  • Researchers reported a lasting loss of diagnostic trust after Theranos.
  • Finger-prick tests are still limited by sampling and sensitivity.
  • Developers emphasised transparency and rigorous evidence over big promises.
MoL Event Pick
HealthSpan Festival 2027 (Valencia, Spain)

HealthSpan Festival 2027

6. OCT 2027 - 7. OCT 2027 - Valencia, SpainFestival

Application-reviewed healthspan festival in Valencia on longevity science, prevention, healthcare delivery and the economics of ageing.

Nature - Main23 Oct 2026
Moderna mRNA vaccine almost halves the risk of skin cancer returning (Nature - Main)

Moderna mRNA vaccine almost halves the risk of skin cancer returning

A phase III trial found intismeran with pembrolizumab reduced melanoma recurrence or death by 42%.

Key takeaways
  • The trial enrolled 1,137 people with stage IIIB–IV melanoma.
  • Individual vaccines were designed by sequencing each patient's tumour.
  • The overall survival outcomes remain uncertain pending longer follow-up.
Nature - Biotechnology23 Oct 2026
Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia (Nature - Biotechno

Gradient-driven microfluidic framework for the screening of ratiometric drug combinations towards precision oncology in paediatric leukaemia

GradientScreen tested overlapping drug ratios and found efficacy and synergy linked to MRD and outcomes.

Key takeaways
  • GradientScreen tested drug combinations in childhood leukaemia samples.
  • Drug-combination results were linked to residual disease and outcomes.
  • These observational findings do not establish improved treatment outcomes.
Frontiers - Health23 Oct 2026
AITraditional Chinese medicine constitution-related body-composition phenotypes and one-year metabolic changes: a repeated health-examination study (Frontiers - H

Traditional Chinese medicine constitution-related body-composition phenotypes and one-year metabolic changes: a repeated health-examination study

Repeated exams found Yang‑deficiency and phlegm‑dampness had lower muscle and higher total and visceral fat.

Key takeaways
  • Yang‑deficiency and phlegm‑dampness were associated with lower muscle mass.
  • Per‑SD rises in total and visceral fat were linked to metabolic clustering.
  • Observed adiposity changes paralleled BMI change and are not causal proof.