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Masters of Longevity - The Pulse

Feature21 Jul 2026

Wellness promised us an easier life, yet gave Us 14 Things to Do Before Breakfast

Recovery should make us feel better — not give us more data, decisions and routines to manage. This opinion asks when self-care became another job, and what health technology should do differently.

A visibly worried person studies a phone whose screen faces away from the viewer, surrounded by wellness devices.

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Latest in Longevity

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Neuroscience News23 Jul 2026
3D Genome Disruption in Alzheimer’s Disease (Neuroscience News)

3D Genome Disruption in Alzheimer’s Disease

3D genome folding in brain cells and its link to gene regulation and tissue organization in Alzheimer’s — an accessible preview of the study’s scope and methods.

Key takeaways
  • Contacts between genes and nearby regulatory elements that help control gene activity also weakened.
  • These architectural alterations were linked to reduced neuronal and synaptic programs.
  • While amyloid plaques and tau tangles are classic hallmarks of Alzheimer’s.
Fight Aging!23 Jul 2026
AIGut Microbiome Composition Correlates with Epigenetic Clock Results (Fight Aging!)

Gut Microbiome Composition Correlates with Epigenetic Clock Results

Report on a proof-of-concept study linking gut microbiome composition to DNA methylation pace-of-aging measures and identifying candidate taxa for follow-up.

Key takeaways
  • Microbiome-based EpiBiome models significantly predicted DunedinPACE at species and genus levels.
  • Bifidobacterium adolescentis was the strongest predictor of decelerated biological aging.
  • Succinivibrio dextrinosolvens showed the strongest association with accelerated biological aging.
Neuroscience News23 Jul 2026
How Midlife Systems Remodeling Reshapes the Human Hippocampus (Neuroscience News)

How Midlife Systems Remodeling Reshapes the Human Hippocampus

Report on cell-type resolved changes in gene regulation and 3D genome structure in the hippocampus beginning in midlife, with an immune and vascular remodeling angle.

Key takeaways
  • Key discovery shows a dramatic shift in the brain’s immune landscape between ages 50 and 75.
  • Midlife human brain aging is driven by a breakdown in 3D genome architecture.
  • Combined with a marked decline in cell populations responsible for maintaining the blood-brain barrier.
PR Newswire23 Jul 2026
AILilac Biosciences and Soin Neuroscience Announce Publication of Clinical Review on RNA Biomarkers for Neuropathic Pain (PR Newswire)

Lilac Biosciences and Soin Neuroscience Announce Publication of Clinical Review on RNA Biomarkers for Neuropathic Pain

A joint clinical review proposes a translational roadmap for using RNA biomarkers to create objective measures for neuropathic pain assessment and monitoring.

Key takeaways
  • Neuropathic pain has historically been difficult to quantify.
  • Company combines clinical research and engineering to develop evidence supported pain management solutions.
  • Ohio-based medical device innovator founded by pain management physician Amol Soin.