Masters of Longevity - The Pulse

Longevity Technology17 Jun 2026
Researchers identify Alzheimer’s immune ‘tipping point’ (Longevity Technology)

Researchers identify Alzheimer’s immune ‘tipping point’

Readers will open a feature examining new scientific research into immune influences on Alzheimer’s and what that means for brain resilience.

Key takeaways
  • Microglia are often described as the brain’s immune cells, or simply the maintenance crew.
  • Those same cells can shift into a different mode – one associated with tau pathology.
  • Much of the field has focused on removing amyloid plaques.
Science Daily - Health & Medicine17 Jun 2026
Humans may have hidden regenerative powers (Science Daily - Health & Medicine)

Humans may have hidden regenerative powers

Examination of research on reawakening mammalian regenerative ability with a staged intervention and implications for restoring complex tissues.

Key takeaways
  • Sequential FGF2 followed by BMP2 treatment stimulated digit regeneration in mice.
  • Two-stage protocol redirected healing away from scarring toward tissue regrowth.
  • Treated mice rebuilt bone, joints, ligaments, and tendons after digit amputation.
PR Newswire17 Jun 2026
AINew Proof-of-Concept Study Explores Acute Cognitive Benefits of Cognizin® (PR Newswire)

New Proof-of-Concept Study Explores Acute Cognitive Benefits of Cognizin®

Preview of a proof-of-concept study examining a single-dose cognitive ingredient's acute effects on brain activity and performance, relevant for formulators.

Key takeaways
  • Randomized double-blind placebo-controlled crossover tested a single 500 mg dose versus placebo.
  • Participants were assessed at 60 and 240 minutes post-ingestion to gauge onset and duration.
  • Outcomes included EEG brain-wave analysis, validated cognitive tasks, and mood assessments.
Longevity Technology17 Jun 2026
AIDual stem cell and anti-aging therapy extends mouse lifespan by over 70% (Longevity Technology)

Dual stem cell and anti-aging therapy extends mouse lifespan by over 70%

Preclinical dual-modality study pairs senolytic immune therapy with stem cell regeneration and examines translational implications for aging interventions.

Key takeaways
  • Collaboration reported more than a 70% lifespan increase in treated mice.
  • Intervention paired immune-based senescent cell clearance with personalized mesenchymal stem cell therapy.
  • Researchers from multiple institutions contributed and the companies said a full manuscript is available.