Masters of Longevity - The Pulse

Frontiers - Health31 May 2026
AIPreoperative nutritional status, frailty, and postoperative delirium in patients undergoing pancreatic cancer surgery: a prospective observational study (Fronti

Preoperative nutritional status, frailty, and postoperative delirium in patients undergoing pancreatic cancer surgery: a prospective observational study

Examine how preoperative nutritional status and frailty relate to postoperative delirium risk following pancreatic cancer surgery, with mediation and predictive analyses.

Key takeaways
  • Postoperative delirium occurred in 19.5% of the study patients.
  • Frailty score independently predicted postoperative delirium with OR 2.451.
  • PNI affected delirium indirectly through frailty and lacked independent predictive value.
PR Newswire30 May 2026
AIWhitehawk Therapeutics Presents Real‑World Analysis Confirming SEZ6 as a Highly Expressed, Clinically Relevant Target for SCLC and Other Neuroendocrine Tumors a

Whitehawk Therapeutics Presents Real‑World Analysis Confirming SEZ6 as a Highly Expressed, Clinically Relevant Target for SCLC and Other Neuroendocrine Tumors at ASCO 2026

Molecular analysis press release describing a real-world RNA study and its intriguing implications for targeting tumor surface proteins in neuroendocrine and lung cancers.

Key takeaways
  • SEZ6 is highly expressed across small cell lung cancer and neuroendocrine tumors.
  • SEZ6 expression exceeds other ADC targets in SCLC and is enriched in neuroendocrine-high subtypes.
  • IND filing is expected mid-2026 with Phase 1 planned to start in Q3 2026.
Neuroscience News30 May 2026
Researchers Use Collagen Tiles to Stop Brain Cancer Recurrence (Neuroscience News)

Researchers Use Collagen Tiles to Stop Brain Cancer Recurrence

Readers curious about brain tumor surgery advances will find a news article examining a randomized clinical trial of implantable collagen tiles used during tumor removal.

Key takeaways
  • TBRT reduced one-year surgical-site recurrence to 1.3% versus 15.4% with SRT.
  • Median overall survival was 42.5 months with TBRT versus 17.6 months with SRT.
  • FDA-cleared cesium-131 collagen tile brachytherapy device was used without increased toxicity.
Youtube — Siim Land30 May 2026
Stanford Scientist: Why Aging Accelerates at 44 and 60 (Youtube — Slim Land)

Stanford Scientist: Why Aging Accelerates at 44 and 60

A genomicist explains why human aging appears to accelerate at midlife and later life and surveys multi-omic tracking plus wearable monitoring tools.

Key takeaways
  • Aging shows accelerated inflection points around ages 44 and 60 according to Snyder.
  • Multi-omic profiling combined with continuous monitoring like CGM and HRV can predict risks.
  • Lifestyle and metabolic interventions are emphasized as more actionable than near-term genetic fixes.