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Will the mRNA flu shot work better than a regular seasonal one? What the science says

Source: Nature - Main • Published: 13 Aug 2026, 00:00

Will the mRNA flu shot work better than a regular seasonal one? What the science says

An analysis of Moderna's newly approved mRNA influenza vaccine and the evidence on its efficacy, safety, and reformulation advantages for seasonal flu control.

Key Takeaways
  • Study also found that mFLUSIVA was well tolerated by most participants
  • Adverse side effects were predominantly mild to moderate
  • It measured participants’ antibody responses to flu rather than flu-like symptoms
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