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Targeted lipid nanoparticles unlock in vivo human haematopoietic stem cell gene editing

Source: Nature - Biotechnology • Published: 21 Aug 2026, 00:00

Targeted lipid nanoparticles unlock in vivo human haematopoietic stem cell gene editing

Describes antibody‑modified lipid nanoparticles that deliver genetic edits directly to human haematopoietic stem cells in bone marrow, enabling in vivo modification.

Key Takeaways
  • Article CAS PubMed Google Scholar Beck, A., Goetsch, L., Dumontet, C
  • Article CAS PubMed Google Scholar Lin, Y., Cheng, Q
  • Article PubMed PubMed Central Google Scholar Du, J
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