News summary

SystImmune, Inc. to Present New Global Data on Iza-bren (izalontamab brengitecan) in EGFR-mutated Non-Small Cell Lung Cancer at WCLC Congress 2026

Source: PR Newswire • Published: 12 Sept 2026, 09:15

Summarized by Masters of Longevity from PR Newswire.

A preview of a conference presentation covering global clinical trial results for a new targeted therapy in EGFR‑mutated lung cancer, highlighting trial design and development plans.

SystImmune, Inc. to Present New Global Data on Iza-bren (izalontamab brengitecan) in EGFR-mutated Non-Small Cell Lung Cancer at WCLC Congress 2026
Key Takeaways
  • Randomized Phase 1 dose-expansion data showed higher efficacy at the 2.5 mg/kg dose level compared with lower doses.
  • Safety and pharmacokinetic findings across global patients supported 2.5 mg/kg D1D8 Q3W as the recommended Phase 3 dose.
  • SystImmune plans a global registrational study named IZABRIGHT-Lung01 in EGFR-mutated NSCLC after prior third-generation EGFR inhibitor treatment.
Read the full article at PR Newswire

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