A new single-cell multiomic method maps chromatin marks, whole transcriptomes, and surface proteins from individual cells to study cell-state transitions and rare samples.
Key Takeaways
- Simultaneous mapping of chromatin states and transcriptomes in rare cell populations is challenging
- 2: OneCell CUT&Tag provides matched transcriptome and epigenome profiling of single zygotes
- Raw sequencing files were submitted to the Gene Expression Omnibus under accession number GSE290486