Summarized by Masters of Longevity from Fight Aging!.
Late‑life semaglutide in mice: a research article examining whether appetite‑reducing treatment produces calorie‑restriction‑like effects on aging and healthspan.

Key Takeaways
- Semaglutide treatment reduced food intake by about 24% in 20-month-old female C57BL/6 mice.
- Treated mice showed improved physiological function and roughly 15% longer lifespan compared with controls.
- Semaglutide reduced ageing hallmarks and mirrored many molecular and physiological effects of matched calorie restriction.



