Summarized by Masters of Longevity from Frontiers - Health.
Nationwide multicenter retrospective cohort describes real-world treatments and bone density changes in pregnancy and lactation-associated osteoporosis across tertiary endocrine centers.
Key Takeaways
- Among 59 women with PLO, 86.4% had vertebral fractures and 67.8% had multiple fractures.
- First-line treatments included teriparatide for 22 patients, bisphosphonates for 10, denosumab for 3, and calcium plus vitamin D for 24 patients.
- Teriparatide produced greater early lumbar spine BMD gains than calcium and vitamin D (19.1% vs 9.5%), but adjusted analyses removed treatment group significance.
