A preclinical research article examining whether adjusting perfusate composition improves outcomes during prolonged ex vivo lung perfusion in a swine model; it previews experimental methods and translational implications.
Key Takeaways
- Twelve porcine lung blocks were harvested and cold-preserved before undergoing 12 h of normothermic EVLP
- Lung blocks were randomly assigned to two groups based on the perfusate replacement strategy
- Left lungs were transplanted during 4 h into donor-related pigs