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Pretransplant albumin-to-globulin ratio and long-term outcomes after liver transplantation for hepatocellular carcinoma: a two-center cohort study

Source: Frontiers - Health • Published: 24 Aug 2026, 00:00

Pretransplant albumin-to-globulin ratio and long-term outcomes after liver transplantation for hepatocellular carcinoma: a two-center cohort study

Examines whether pretransplant albumin-to-globulin ratio improves long-term survival and recurrence prediction after liver transplantation for HCC.

Key Takeaways
  • Development cohort included 254 adults undergoing first liver transplantation for pathologically confirmed HCC
  • Five nutritional indices were compared using Kaplan-Meier estimates, Cox regression, and restricted cubic splines
  • Time-dependent ROC curves included bootstrap 95% confidence intervals
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