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Predicting Unfavorable Response to Initial Radioactive Iodine Therapy in Differentiated Thyroid Cancer: An Explainable Machine Learning and Survival Analysis Approach

Source: Frontiers - Health • Published: 19 Aug 2026, 00:00

Predicting Unfavorable Response to Initial Radioactive Iodine Therapy in Differentiated Thyroid Cancer: An Explainable Machine Learning and Survival Analysis Approach

Assessment of combining pre-therapy and early post-therapy clinical data with machine learning to predict poor responses after initial radioactive iodine treatment for differentiated thyroid cancer.

Key Takeaways
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  • Methods:We retrospectively included 550 patients with DTC who underwent total thyroidectomy followed by initial RAIT
  • Demographic, pathological, imaging, and biochemical data were collected
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