A study characterizes thermoresponsive PNIPAM nanogels and reports their physicochemical properties and in vitro biocompatibility for drug delivery applications.
Key Takeaways
- PNIPAM nanogels showed a hydrodynamic diameter around 138 nm and near-neutral surface charge
- Nanogels had a lower critical solution temperature close to physiological temperature
- In vitro tests showed hemolysis below 5% and over 90% cell viability across several cell lines