Review summarizes evidence on MMP-7 as a circulating biomarker across fibrosing interstitial lung diseases and other chronic respiratory disorders.
Key Takeaways
- MMP-7 shows strong diagnostic and prognostic performance in idiopathic pulmonary fibrosis
- Elevated MMP-7 levels correlate with fibrosis and reduced lung function in connective tissue disease‑associated ILD
- MMP-7 reflects epithelial injury and matrix remodeling and is best used within multimarker strategies