News summary

Minicircle’s gene therapy advances in XPRIZE $101m aging race

Source: Longevity Technology • Published: 22 Sept 2026, 17:03

Summarized by Masters of Longevity from Longevity Technology.

Profile of a preclinical plasmid gene therapy company that reached the XPRIZE Healthspan final ten and plans a large placebo-controlled human trial testing multi-gene interventions for aging-related decline.

Minicircle’s gene therapy advances in XPRIZE $101m aging race
Key Takeaways
  • Minicircle was named one of ten XPRIZE Healthspan Milestone 2 finalists and received $1 million in funding.
  • The company develops non-viral minicircle DNA vectors delivering genes without genomic integration and targets reversible subcutaneous administration.
  • Lead candidate Follistatin (FST-344) aims to enhance muscle mass and metabolic health while a Klotho program is planned for 2026.
Read the full article at Longevity Technology

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