Longevity News

Mild autonomous cortisol secretion and brain function: cognitive, structural, and functional correlates

Source: Frontiers - Health • Published: 20 Aug 2026, 00:00

Mild autonomous cortisol secretion and brain function: cognitive, structural, and functional correlates

Reports combined structural and resting-state functional MRI with cognitive and sleep assessments to compare brain function in patients with mild autonomous cortisol secretion and non-functioning adrenal tumors.

Key Takeaways
  • Patients with MACS also showed significantly poorer sleep quality
  • No group differences were observed in depressive symptoms
  • Resting-state fMRI revealed altered hippocampal connectivity in MACS
Read Original Source