Hidradenitis suppurativa examined through immunometabolic and clinical lenses, previewing research that links systemic metabolism and immune mechanisms to disease pathways.
Key Takeaways
- HS is framed as a systemic disorder linked to obesity, insulin resistance, and cardiovascular disease
- Myosteatosis, not sarcopenia, was independently associated with HS in a CT-based study
- CD4+ memory T-cell reorganization and the TL1A-DR3 axis were identified as potential mechanistic and therapeutic targets