Longevity News

Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes in Breast Cancer Histopathology: A Systematic Review and Evidence-Gap Analysis of Translational Readiness

Source: Frontiers - Health • Published: 22 Aug 2026, 00:00

Machine Learning-Based Assessment of Tumor-Infiltrating Lymphocytes in Breast Cancer Histopathology: A Systematic Review and Evidence-Gap Analysis of Translational Readiness

Assessments of tumor-infiltrating lymphocytes in breast cancer using machine learning are reviewed and mapped for translational readiness and methodological gaps.

Key Takeaways
  • Review mapped 51 histopathology-image ML studies across detection, prognostication, and treatment-response prediction
  • External validation was reported in 31.6% of detection
  • Calibration and decision-curve analysis were nearly absent, with calibration reported in only one prognostication study
Read Original Source