Summarized by Masters of Longevity from Frontiers - Health.
Ketones and brain health — a short review exploring how intermittent mild ketosis might function as a normal metabolic switch that promotes long-term cerebral resilience and adaptability.
Key Takeaways
- Intermittent, mild physiological ketosis can enhance cerebral metabolic flexibility by increasing brain ketone utilization capacity.
- Ketone bodies enter and are oxidized by brain cells via monocarboxylate transporters, which adaptively increase with sustained ketone exposure.
- Regularly alternating glucose and ketone fuel use may activate mitochondrial, antioxidant, and neurotrophic pathways that support long-term brain resilience.
