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Interplay between monocyte subsets and leukemic blasts shapes the immune microenvironment and sustains minimal residual disease in pediatric B-cell acute lymphoblastic leukemia

Source: Frontiers - Health • Published: 18 Aug 2026, 00:00

Interplay between monocyte subsets and leukemic blasts shapes the immune microenvironment and sustains minimal residual disease in pediatric B-cell acute lymphoblastic leukemia

Reports single-cell and clinical analyses linking monocyte subset shifts and IFN-responsive leukemic clones to persistent minimal residual disease in pediatric B-ALL.

Key Takeaways
  • Department of Pediatrics, Sheng Jing Hospital Affiliated, China Medical University, Shenyang, China 2
  • Medical Research Center, Sheng Jing Hospital Affiliated, China Medical University, Shenyang, China 3
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