This article examines acute inflammatory and neurotrauma biomarker patterns in combat casualties and how such profiles could guide clinical triage and resource planning.
Key Takeaways
- Multiple inflammatory cytokines and DAMPs were significantly elevated in serum after combat injuries
- Specific biomarkers varied by injury type, for example eNAMPT and TNF-α were higher in penetrating wounds
- Levels of IL-1RA, IL-6, eNAMPT, and S100A8 correlated with ventilator days, hospital stay, and ICU duration