Report on longitudinal changes in IgG glycosylation in active lupus nephritis patients during the first year of immunosuppressive therapy, focusing on shifts from active to treated disease.
Key Takeaways
- Is a severe manifestation of systemic lupus erythematosus (SLE)
- SLE disproportionately affects women, with an estimated female-to-male prevalence ratio of approximately 9:1 ( 1 , 2 )
- Each IgG molecule contains a conserved N-glycosylation site