Summarized by Masters of Longevity from Youtube — Siim Land.
A first-person experiment and evidence roundup about whether a reduced creatine megadose helps protect thinking and energy during sleep loss; a practical, curiosity-driven look at dosing and real-world effects.
Key Takeaways
- A 0.2 g/kg creatine dose (about 15 g for the creator) reduced cognitive decline after restricted sleep compared with no supplement.
- A prior 0.35 g/kg dose (about 28 g) produced larger effects in the original study, indicating dose response for sleep-deprivation benefit.
- A 2024 meta-analysis of 16 RCTs found no significant overall cognition improvement in healthy, well‑rested people, but small memory gains were reported.
