Summarized by Masters of Longevity from Fight Aging!.
This article previews a mouse biology study testing growth-hormone receptor antagonism and its potential to modestly slow aging and improve late-life health.
Key Takeaways
- Genetic conversion of growth hormone into a receptor antagonist extended median and maximal lifespan in both male and female mice.
- Maximal lifespan increased by about 186 days in males and 265 days in females compared with controls.
- Two-year-old antagonist mice showed reduced frailty and improved grip strength despite higher adiposity.
