Summarized by Masters of Longevity from Longevity Technology.
Reports that a centenarian SIRT6 gene therapy reduced biological age in senior beagles and improved secondary functional measures in a randomized blinded trial.
Key Takeaways
- Genflow's SLAB trial randomized 24 beagles over age 10 and met its primary endpoint based on the GRIM DNA methylation clock.
- Treated dogs showed earlier positive muscle data and sustained safety and efficacy at a three-month follow-up.
- Genflow is discussing licensing and commercialization with major animal health companies to pursue veterinary pathways to market.
