Summarized by Masters of Longevity from Fight Aging!.
A newsletter surveys recent longevity research, focusing on comparative analyses of epigenetic aging clocks and immune drivers of early atherosclerosis.
Key Takeaways
- A harmonized TranslAGE database compiled 51 longitudinal interventional studies and calculated 16 epigenetic clocks plus 94 DNAm biomarkers for each study.
- Clocks trained to predict mortality or pace of aging showed the strongest and most consistent responses across diverse interventions.
- Pharmacological and lifestyle interventions produced the largest DNAm biomarker changes, with study population and duration strongly affecting responsiveness.
