Telomere biology and neuroinflammation research updates: a newsletter surveying experimental antisense telomere therapies and a short‑acting PD‑L1 antibody trial, with context on aging biology and therapeutic challenges.
Key Takeaways
- Persistent tDDR drives cellular senescence and cell death
- Here we show in telomerase-deficient Telomerase RNA component (TERC)
- Similar observations were recapitulated in aged wild-type mice