Cellular senescence in the aging brain: an accessible preview of a study mapping which brain cell types signal and spread senescence, and why that matters for therapeutic targeting.
Key Takeaways
- Like most of the progression of degenerative aging, the accumulation of senescent cells with age is nonlinear
- This is in part because the decline of the immune system accelerates in later life
- Which can propagate senescence in neighboring cells both in vitro and in vivo