News summary

Evaluation of pH-responsive release behavior, antioxidant activity and cytotoxic potential of quercetin-loaded sodium alginate gellan gum hydrogel beads

Source: Nature - Biotechnology • Published: 10 Sept 2026, 00:00

Summarized by Masters of Longevity from Nature - Biotechnology.

Assess a pH-responsive bio-based polymer delivery matrix for antioxidant release, storage stability, and cytotoxicity evaluation in vitro.

Evaluation of pH-responsive release behavior, antioxidant activity and cytotoxic potential of quercetin-loaded sodium alginate gellan gum hydrogel beads
Key Takeaways
  • Two alginate-gellan formulations showed encapsulation efficiencies of 84.3% and 93.26% respectively.
  • Simulated intestinal fluid released roughly 35–37% of the antioxidant after eight hours.
  • Cell assays found free antioxidant IC80 at 32.7 ppm versus bead extracts at ~147 ppm.
Read the full article at Nature - Biotechnology

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