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Computational activation of CISD3 by a novel flavonoid compound for cardiac ageing and cardiovascular health

Source: Nature - Biotechnology • Published: 25 Aug 2026, 00:00

Computational activation of CISD3 by a novel flavonoid compound for cardiac ageing and cardiovascular health

This article previews a computational drug‑discovery study proposing a novel flavonoid as a candidate activator of a mitochondrial protein linked to cardiac ageing. It invites readers interested in molecular modelling, cardiometabolic interventions, and preclinical therapeutic strategies.

Key Takeaways
  • It is citable and carries a permanent DOI
  • This version is subject to further edits and will be replaced automatically by the final Version of Record
  • Characterised by a 2Fe–2 S cluster and localized in the outer mitochondrial membrane
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