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Feature20 Oct 2026

MOTS-c: Where the Evidence Ends

Studies offer clues about ageing and metabolism. What do they actually tell us about human health—and where does expert opinion take over?

MOTS-c: Where the Evidence Ends

By The Peptide Dosing editorial team

Studies offer clues about ageing and metabolism. What do they actually tell us about human health—and where does expert opinion take over?

Feature20 Oct 2026
Abstract illustration of mitochondria with folded inner membranes in a cell

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  2. 02Final OS Analysis Results from Phase III OptiTROP-Lung04 Study of Sacituzumab Tirumotecan (sac-TMT) Presented at 2026 ESMO (PR Newswire)Final OS Analysis Results from Phase III OptiTROP-Lung04 Study of Sacituzumab Tirumotecan (sac-TMT) Presented at 2026 ESMOPR Newswire • 25 Oct 2026External link, opens in a new tab
  3. 03The Results of Phase III OptiTROP-Lung06 Study of Sacituzumab Tirumotecan (sac-TMT) Presented as an ESMO Oral Presentation and Simultaneous... (PR Newswire)The Results of Phase III OptiTROP-Lung06 Study of Sacituzumab Tirumotecan (sac-TMT) Presented as an ESMO Oral Presentation and Simultaneously Published in The New England Journal of MedicinePR Newswire • 25 Oct 2026External link, opens in a new tab
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  5. 05Urinary succinate is associated with kidney injury in type 2 diabetes mellitus: a cross-sectional analysis (Frontiers - Health)Urinary succinate is associated with kidney injury in type 2 diabetes mellitus: a cross-sectional analysisFrontiers - Health • 26 Oct 2026External link, opens in a new tab

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  1. THE LIVE Barcelona 2026 (Barcelona, Spain)26. OCT 2026 - 28. OCT 2026THE LIVE Barcelona 2026Media PartnerSummit - Barcelona, Spain★
  2. CEE Longevity Summit & Retreat 2026 (Samorin, Slovakia)29. OCT 2026 - 31. OCT 2026CEE Longevity Summit & Retreat 2026Retreat - Samorin, Slovakia
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  4. Biology of Aging Symposium V 2026: The Possibilities of Aging and Health (Montreal, Canada)1. NOV 2026 - 3. NOV 2026Biology of Aging Symposium V 2026: The Possibilities of Aging and HealthConference - Montreal, Canada
  5. Atlas Cove Longevity Residency — November 2026 (Setúbal, Portugal)1. NOV 2026 - 6. NOV 2026Atlas Cove Longevity Residency — November 2026Retreat - Setúbal, Portugal

Latest in Longevity

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Science Daily - Health & Medicine23 Oct 2026
Scientists discover a surprising double benefit of exercise for Parkinson’s (Science Daily - Health & Medicine)

Scientists discover a surprising double benefit of exercise for Parkinson’s

An observational cohort found greater baseline activity tied to slower motor and cognitive progression over seven years.

Key takeaways
  • Greater baseline activity was linked to slower motor decline.
  • Greater baseline activity was linked to slower cognitive decline.
  • These observational results are not proof of cause and effect.
Longevity Technology23 Oct 2026
AICognition Therapeutics gets FDA alignment for Phase 3 Zervimesine trial (Longevity Technology)

Cognition Therapeutics gets FDA alignment for Phase 3 Zervimesine trial

FDA and Cognition Therapeutics agreed Phase 3 CT1812 endpoints for DLB patients.

Key takeaways
  • The primary endpoint is NPI-2 assessing hallucinations and delusions.
  • A key secondary endpoint is ADCS-ADL measuring daily function.
  • Regulatory alignment was reached but does not prove drug efficacy.
Longevity Technology23 Oct 2026
Mind the gap: pregnancy, recovery and the aging clock (Longevity Technology)

Mind the gap: pregnancy, recovery and the aging clock

Review and small studies found pregnancy elevated biological-age markers that largely declined after recovery.

Key takeaways
  • Pregnancy was associated with higher biological-age readings in studies.
  • Sleep, stress, breastfeeding and BMI were linked to recovery differences.
  • Evidence is observational and modest, so causation is unproven.
MoL Event Pick
HealthSpan Festival 2027 (Valencia, Spain)

HealthSpan Festival 2027

6. OCT 2027 - 7. OCT 2027 - Valencia, SpainFestival

Application-reviewed healthspan festival in Valencia on longevity science, prevention, healthcare delivery and the economics of ageing.

Register