Read a transcriptomic study of how a zinc-containing mouth rinse alters oral cell inflammatory signaling and stress-response gene programs.
Key Takeaways
- IL-1β and TNF-α induced a broad inflammatory transcription dominated by chemokines and interferon genes
- Zinc-containing rinse selectively suppressed interferon-associated genes including CXCL10 and IFIT family members
- Zinc was the predominant metal and zinc alone partially reproduced CXCL10 suppression