Tooth agenesis and colorectal cancer risk — a systematic review you can open to learn whether dental developmental patterns are studied as a clinical risk signal, who’s been studied, and what types of evidence inform targeted screening considerations.
Key Takeaways
- Registry and genetically defined cohorts show stronger associations between tooth agenesis and colorectal cancer risk
- Pathogenic AXIN2 variants are linked with oligodontia and markedly higher colorectal neoplasia odds
- Tooth agenesis is not a recommended universal screening marker because common hypodontia yields high false positives