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The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value

Source: Frontiers - Health • Published: 03 Jul 2026, 00:00

The mediating effect of DHA-mediated MPV improvement on coronary artery stenosis and its prognostic value

This clinical study explores links between nutritional blood markers and platelet characteristics in relation to coronary artery narrowing, using mediation and prognostic analyses.

Key Takeaways
  • Mean platelet volume is highlighted as an accessible biomarker linked to lesion severity and MACE
  • Cohort included 183 CAD patients with median 38 months follow-up and complete outcomes
  • Analysis tested serum DHA and EPA associations with Gensini score and MPV mediation
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