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The impact of pretransplant consolidation chemotherapy on clinical outcomes in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a single-center retrospective study

Source: Frontiers - Health • Published: 15 Jul 2026, 00:00

The impact of pretransplant consolidation chemotherapy on clinical outcomes in adult patients with Philadelphia chromosome-negative acute lymphoblastic leukemia: a single-center retrospective study

Reports a single-center retrospective comparison of one versus multiple pretransplant consolidation chemotherapy cycles in adult Philadelphia chromosome-negative ALL and their clinical outcomes.

Key Takeaways
  • Though pretransplant consolidation chemotherapy is generally considered essential
  • Who underwent allo-HSCT at our center between January 2014 and May 2025
  • Eighteen received a single cycle of consolidation chemotherapy prior to transplant
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